A dual function of NKG2D ligands in NK-cell activation

NK-cell killing requires both the expression of activating receptor ligands and low MHC class I expression by target cells. Here we demonstrate that the expression of any of the murine ligands for the NK-cell activating receptor NKG2D results in a concomitant reduction in MHC class I expression. We...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cheney, Elizabeth E., Wise, Erica L., Bui, Jack D., Schreiber, Robert D., Carayannopoulos, Leonidas N., Spitzer, Dirk, Zafirova, Biljana, Polic, Bojan, Shaw, Andrey S., Markiewicz, Mary A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641666/
https://ncbi.nlm.nih.gov/pubmed/22740149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201141849
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