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Dedifferentiation into blastomere-like cancer stem cells via formation of polyploid giant cancer cells
Our recent perplexing findings that polyploid giant cancer cells (PGCCs) acquired embryonic-like stemness and were capable of tumor initiation raised two important unanswered questions: how do PGCCs acquire such stemness, and to which stage of normal development do PGCCs correspond. Intriguingly, fo...
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| Publicado en: | Oncogene |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5582213/ https://ncbi.nlm.nih.gov/pubmed/28436947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.72 |
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