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Coevolution of neoplastic epithelial cells and multilineage stroma via polyploid giant cells during immortalization and transformation of mullerian epithelial cells

Stromal cells are generally considered to be derived primarily from the host's normal mesenchymal stromal cells or bone marrow. However, the origins of stromal cells have been quite controversial. To determine the role of polyploidy in tumor development, we examined the fate of normal mullerian...

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Detalhes bibliográficos
Publicado no:Genes Cancer
Main Authors: Zhang, Shiwu, Mercado-Uribe, Imelda, Sood, Anil, Bast, Robert C., Liu, Jinsong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918945/
https://ncbi.nlm.nih.gov/pubmed/27382431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/genesandcancer.102
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