Paclitaxel Inhibits Ovarian Tumor Growth by Inducing Epithelial Cancer Cells to Benign Fibroblast-like cells

Paclitaxel is commonly used to treat multiple human malignancies, but its mechanism of action is still poorly defined. Human ovarian cancer SKOV3 cells (parental SKOV3) were treated with paclitaxel (1 μM) for 2 days, and the morphologic changes in the cells were monitored for more than 4 months. Par...

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Hlavní autoři: Jia, Lizhou, Zhang, Shiwu, Ye, Yanfen, Li, Xin, Mercado-Uribe, Imelda, Bast, Robert C., Liu, Jinsong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495569/
https://ncbi.nlm.nih.gov/pubmed/22902993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2012.08.004
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