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Dedifferentiation into blastomere-like cancer stem cells via formation of polyploid giant cancer cells

Our recent perplexing findings that polyploid giant cancer cells (PGCCs) acquired embryonic-like stemness and were capable of tumor initiation raised two important unanswered questions: how do PGCCs acquire such stemness, and to which stage of normal development do PGCCs correspond. Intriguingly, fo...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Oncogene
Päätekijät: Niu, N, Mercado-Uribe, I, Liu, J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582213/
https://ncbi.nlm.nih.gov/pubmed/28436947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.72
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