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Dedifferentiation into blastomere-like cancer stem cells via formation of polyploid giant cancer cells
Our recent perplexing findings that polyploid giant cancer cells (PGCCs) acquired embryonic-like stemness and were capable of tumor initiation raised two important unanswered questions: how do PGCCs acquire such stemness, and to which stage of normal development do PGCCs correspond. Intriguingly, fo...
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Publicado no: | Oncogene |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5582213/ https://ncbi.nlm.nih.gov/pubmed/28436947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.72 |
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