RIG-I overexpression decreases mortality of cigarette smoke exposed mice during influenza A virus infection

BACKGROUND: Retinoic acid-inducible gene I (RIG-I) is an important regulator of virus-induced antiviral interferons (IFNs) and proinflammatory cytokines which participate in clearing viral infections. Cigarette smoke (CS) exposure increases the frequency and severity of respiratory tract infections....

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Wang, Xiaoqiu, Wu, Wenxin, Zhang, Wei, Leland Booth, J., Duggan, Elizabeth S., Tian, Lili, More, Sunil, Zhao, Yan D., Sawh, Ravindranauth N., Liu, Lin, Zou, Ming-Hui, Metcalf, Jordan P.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581920/
https://ncbi.nlm.nih.gov/pubmed/28865477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-017-0649-z
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