Cigarette smoke extract suppresses the RIG-I-initiated innate immune response to influenza virus in the human lung

Cigarette smoking is the major cause of chronic obstructive pulmonary disease (COPD) and predisposes subjects to severe respiratory tract infections. Epidemiological studies have shown that cigarette smokers are seven times more likely to contract influenza infection than nonsmokers. The mechanisms...

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Detalhes bibliográficos
Main Authors: Wu, Wenxin, Patel, Krupa B., Booth, J. Leland, Zhang, Wei, Metcalf, Jordan P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Call for Papers: Cigarette Smoke-Induced Lung Endothelial and Alveolar Epithelial Injury
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119130/
https://ncbi.nlm.nih.gov/pubmed/21335520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00267.2010
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