Cigarette smoke attenuates the RIG-I-initiated innate antiviral response to influenza infection in two murine models

Cigarette smoke (CS) exposure increases the frequency and severity of respiratory tract infections. Despite this association, the mechanisms underlying the increased susceptibility to respiratory virus infection are poorly understood. Retinoic acid-inducible gene I (RIG-I) is an important regulator...

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Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Wu, Wenxin, Zhang, Wei, More, Sunil, Booth, J. Leland, Duggan, Elizabeth S., Liu, Lin, Zhao, Yan D., Metcalf, Jordan P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254961/
https://ncbi.nlm.nih.gov/pubmed/25260755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00158.2014
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