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RIG-I and TLR3 are both required for maximum interferon induction by influenza virus in human lung alveolar epithelial cells

Pattern recognition receptors, such as retinoic acid-inducible protein I (RIG-I), Toll-like receptors 3 and 7 (TLR3 and 7), and nucleotide-binding oligomerization domain containing protein 2 (NOD2), play important roles in the recognition of influenza A virus (IAV), but their role in interferon (IFN...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Wu, Wenxin, Zhang, Wei, Duggan, Elizabeth S., Booth, J. Leland, Zou, Ming-Hui, Metcalf, Jordan P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461467/
https://ncbi.nlm.nih.gov/pubmed/25880109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.03.048
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