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Apolipoprotein C-III inhibits triglyceride hydrolysis by GPIHBP1-bound LPL

apoC-III is often assumed to retard the intravascular processing of triglyceride-rich lipoproteins (TRLs) by inhibiting LPL, but that view is based largely on studies of free LPL. We now recognize that intravascular LPL is neither free nor loosely bound, but instead is tightly bound to glycosylphosp...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Larsson, Mikael, Allan, Christopher M., Jung, Rachel S., Heizer, Patrick J., Beigneux, Anne P., Young, Stephen G., Fong, Loren G.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580902/
https://ncbi.nlm.nih.gov/pubmed/28694296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M078220
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