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The GPIHBP1–LPL complex is responsible for the margination of triglyceride-rich lipoproteins in capillaries

Triglyceride-rich lipoproteins (TRLs) undergo lipolysis by lipoprotein lipase (LPL), an enzyme that is transported to the capillary lumen by an endothelial cell protein, GPIHBP1. For LPL-mediated lipolysis to occur, TRLs must bind to the lumen of capillaries. This process is often assumed to involve...

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Detalhes bibliográficos
Main Authors: Goulbourne, Chris N., Gin, Peter, Tatar, Angelica, Nobumori, Chika, Hoenger, Andreas, Jiang, Haibo, Grovenor, Chris R. M., Adeyo, Oludotun, Esko, Jeffrey D., Goldberg, Ira J., Reue, Karen, Tontonoz, Peter, Bensadoun, André, Beigneux, Anne P., Young, Stephen G., Fong, Loren G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143151/
https://ncbi.nlm.nih.gov/pubmed/24726386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.01.017
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