Equivalent binding of wild-type lipoprotein lipase (LPL) and S447X-LPL to GPIHBP1, the endothelial cell LPL transporter

The S447X polymorphism in lipoprotein lipase (LPL), which shortens LPL by two amino acids, is associated with low plasma triglyceride levels and reduced risk for coronary heart disease. S447X carriers have higher LPL levels in the pre- and post-heparin plasma, raising the possibility that the S447X...

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Détails bibliographiques
Auteurs principaux: Turlo, Kirsten, Leung, Calvin S., Seo, Jane J., Goulbourne, Chris N., Adeyo, Oludotun, Gin, Peter, Voss, Constance, Bensadoun, André, Fong, Loren G., Young, Stephen G., Beigneux, Anne P.
Format: Artigo
Langue:Inglês
Publié: 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4212522/
https://ncbi.nlm.nih.gov/pubmed/24704550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2014.03.011
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