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Movement disorder in GNAO1 encephalopathy associated with gain-of-function mutations

OBJECTIVE: To define molecular mechanisms underlying the clinical spectrum of epilepsy and movement disorder in individuals with de novo mutations in the GNAO1 gene. METHODS: We identified all GNAO1 mutations reported in individuals with epilepsy (early infantile epileptiform encephalopathy 17) or m...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neurology
Prif Awduron: Feng, Huijie, Sjögren, Benita, Karaj, Behirda, Shaw, Vincent, Gezer, Aysegul, Neubig, Richard R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Lippincott Williams & Wilkins 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580866/
https://ncbi.nlm.nih.gov/pubmed/28747448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000004262
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