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Detection of nucleotide disbalance in cells undergoing oncogene-induced senescence
DNA damage response has been characterized as an important mediator of senescence phenotypes induced by activated oncogenes in normal human cells. Depletion of intracellular deoxyribonucleotide pools has been recently recognized as one of the major causes for DNA damage in these cells. Cells undergo...
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| Udgivet i: | Methods Mol Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5579839/ https://ncbi.nlm.nih.gov/pubmed/27812878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-6670-7_16 |
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