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Controversial aspects of oncogene-induced senescence

Oncogene-induced senescence (OIS) is a fail-safe mechanism that is developed to suppress cell proliferation caused by aberrant activation of oncoproteins in normal cells. Most of the available literature considers senescence to be caused by activated RAS or RAF proteins. In the current review, we wi...

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Detalhes bibliográficos
Main Authors: Bianchi-Smiraglia, Anna, Nikiforov, Mikhail A.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524210/
https://ncbi.nlm.nih.gov/pubmed/23095636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.22589
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