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Controversial aspects of oncogene-induced senescence

Oncogene-induced senescence (OIS) is a fail-safe mechanism that is developed to suppress cell proliferation caused by aberrant activation of oncoproteins in normal cells. Most of the available literature considers senescence to be caused by activated RAS or RAF proteins. In the current review, we wi...

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Autors principals: Bianchi-Smiraglia, Anna, Nikiforov, Mikhail A.
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524210/
https://ncbi.nlm.nih.gov/pubmed/23095636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.22589
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