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Identification of amino acid residues involved in the dRP-lyase activity of human Pol ι
Besides X-family DNA polymerases (first of all, Pol β) several other human DNA polymerases from Y- and A- families were shown to possess the dRP-lyase activity and could serve as backup polymerases in base excision repair (Pol ι, Rev1, Pol γ and Pol θ). However the exact position of the active sites...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5579206/ https://ncbi.nlm.nih.gov/pubmed/28860552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10668-5 |
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