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The Mechanistic Links between Insulin and Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Cl(−) Channel

The cystic fibrosis transmembrane conductance regulator (CFTR) Cl(−) channel belongs to the ATP-binding cassette (ABC) transporter superfamily and regulates Cl(−) secretion in epithelial cells for water secretion. Loss-of-function mutations to the CFTR gene cause dehydrated mucus on the apical side...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteur: Marunaka, Yoshinori
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578156/
https://ncbi.nlm.nih.gov/pubmed/28805732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18081767
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