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Chemical Modifications of Nucleic Acid Aptamers for Therapeutic Purposes
Nucleic acid aptamers have minimal immunogenicity, high chemical synthesis production, low cost and high chemical stability when compared with antibodies. However, the susceptibility to nuclease degradation, rapid excretion through renal filtration and insufficient binding affinity hindered their de...
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| Publicado no: | Int J Mol Sci |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5578073/ https://ncbi.nlm.nih.gov/pubmed/28767098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18081683 |
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