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Molecular Selection, Modification and Development of Therapeutic Oligonucleotide Aptamers
Monoclonal antibodies are the dominant agents used in inhibition of biological target molecules for disease therapeutics, but there are concerns of immunogenicity, production, cost and stability. Oligonucleotide aptamers have comparable affinity and specificity to targets with monoclonal antibodies...
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| Publicado no: | Int J Mol Sci |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4813219/ https://ncbi.nlm.nih.gov/pubmed/26978355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17030358 |
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