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Molecular Selection, Modification and Development of Therapeutic Oligonucleotide Aptamers

Monoclonal antibodies are the dominant agents used in inhibition of biological target molecules for disease therapeutics, but there are concerns of immunogenicity, production, cost and stability. Oligonucleotide aptamers have comparable affinity and specificity to targets with monoclonal antibodies...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Mol Sci
Prif Awduron: Yu, Yuanyuan, Liang, Chao, Lv, Quanxia, Li, Defang, Xu, Xuegong, Liu, Baoqin, Lu, Aiping, Zhang, Ge
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813219/
https://ncbi.nlm.nih.gov/pubmed/26978355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17030358
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