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Molecular Selection, Modification and Development of Therapeutic Oligonucleotide Aptamers

Monoclonal antibodies are the dominant agents used in inhibition of biological target molecules for disease therapeutics, but there are concerns of immunogenicity, production, cost and stability. Oligonucleotide aptamers have comparable affinity and specificity to targets with monoclonal antibodies...

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Bibliografiska uppgifter
I publikationen:Int J Mol Sci
Huvudupphovsmän: Yu, Yuanyuan, Liang, Chao, Lv, Quanxia, Li, Defang, Xu, Xuegong, Liu, Baoqin, Lu, Aiping, Zhang, Ge
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813219/
https://ncbi.nlm.nih.gov/pubmed/26978355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17030358
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