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Molecular Selection, Modification and Development of Therapeutic Oligonucleotide Aptamers

Monoclonal antibodies are the dominant agents used in inhibition of biological target molecules for disease therapeutics, but there are concerns of immunogenicity, production, cost and stability. Oligonucleotide aptamers have comparable affinity and specificity to targets with monoclonal antibodies...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Int J Mol Sci
Päätekijät: Yu, Yuanyuan, Liang, Chao, Lv, Quanxia, Li, Defang, Xu, Xuegong, Liu, Baoqin, Lu, Aiping, Zhang, Ge
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813219/
https://ncbi.nlm.nih.gov/pubmed/26978355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17030358
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