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Nucleic Acid Aptamers for Target Validation and Therapeutic Applications

In the simplest view, aptamers can be thought of as nucleic acid analogs to antibodies. They are able to bind specifically to proteins, and, in many cases, that binding leads to a modulation of protein activity. New aptamers are rapidly generated through the SELEX (Systematic Evolution of Ligands by...

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Bibliografski detalji
Glavni autori: Pendergrast, P. Shannon, Marsh, H. Nicholas, Grate, Dilara, Healy, Judith M., Stanton, Martin
Format: Artigo
Jezik:Inglês
Izdano: The Association of Biomolecular Resource Facilities 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291729/
https://ncbi.nlm.nih.gov/pubmed/16461946
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