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Nucleic acid aptamers for targeting of shRNA-based cancer therapeutics

Aptamers are nucleic acid ligands which have been validated to bind to epitopes with a specificity similar to that of monoclonal antibodies. Aptamers have been primarily investigated for their direct function in terms of inhibition of protein targets; however, recent evidence gives reason to activel...

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Détails bibliographiques
Auteurs principaux: Vorhies, John S, Nemunaitis, John J
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721292/
https://ncbi.nlm.nih.gov/pubmed/19707307
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