An Immunogenic Personal Neoantigen Vaccine for Melanoma Patients

Effective anti-tumor immunity in humans has been associated with the presence of T cells directed at cancer neoantigens(1), which are T cell epitopes with tumor-specific expression arising from non-silent somatic mutations. They are highly immunogenic because they are not expressed in normal tissues...

詳細記述

保存先:
書誌詳細
出版年:Nature
主要な著者: Ott, Patrick A., Hu, Zhuting, Keskin, Derin B., Shukla, Sachet A., Sun, Jing, Bozym, David J., Zhang, Wandi, Luoma, Adrienne, Giobbie-Hurder, Anita, Peter, Lauren, Chen, Christina, Olive, Oriol, Carter, Todd A., Li, Shuqiang, Lieb, David J., Eisenhaure, Thomas, Gjini, Evisa, Stevens, Jonathan, Lane, William J., Javeri, Indu, Nellaiappan, Kaliappanadar, Salazar, Andreas, Daley, Heather, Seaman, Michael, Buchbinder, Elizabeth I., Yoon, Charles H., Harden, Maegan, Lennon, Niall, Gabriel, Stacey, Rodig, Scott J., Barouch, Dan H., Aster, Jon C., Getz, Gad, Wucherpfennig, Kai, Neuberg, Donna, Ritz, Jerome, Lander, Eric S., Fritsch, Edward F., Hacohen, Nir, Wu, Catherine J.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577644/
https://ncbi.nlm.nih.gov/pubmed/28678778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22991
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料