An Immunogenic Personal Neoantigen Vaccine for Melanoma Patients

Effective anti-tumor immunity in humans has been associated with the presence of T cells directed at cancer neoantigens(1), which are T cell epitopes with tumor-specific expression arising from non-silent somatic mutations. They are highly immunogenic because they are not expressed in normal tissues...

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Xehetasun bibliografikoak
Argitaratua izan da:Nature
Egile Nagusiak: Ott, Patrick A., Hu, Zhuting, Keskin, Derin B., Shukla, Sachet A., Sun, Jing, Bozym, David J., Zhang, Wandi, Luoma, Adrienne, Giobbie-Hurder, Anita, Peter, Lauren, Chen, Christina, Olive, Oriol, Carter, Todd A., Li, Shuqiang, Lieb, David J., Eisenhaure, Thomas, Gjini, Evisa, Stevens, Jonathan, Lane, William J., Javeri, Indu, Nellaiappan, Kaliappanadar, Salazar, Andreas, Daley, Heather, Seaman, Michael, Buchbinder, Elizabeth I., Yoon, Charles H., Harden, Maegan, Lennon, Niall, Gabriel, Stacey, Rodig, Scott J., Barouch, Dan H., Aster, Jon C., Getz, Gad, Wucherpfennig, Kai, Neuberg, Donna, Ritz, Jerome, Lander, Eric S., Fritsch, Edward F., Hacohen, Nir, Wu, Catherine J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577644/
https://ncbi.nlm.nih.gov/pubmed/28678778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22991
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