Genetic Analysis in UK Biobank Links Insulin Resistance and Transendothelial Migration Pathways to Coronary Artery Disease

UK Biobank is among the world’s largest repositories for phenotypic and genotypic information in individuals of European ancestry(1). We performed a genome-wide association study in UK Biobank testing ~9 million DNA sequence variants for association with coronary artery disease (4,831 cases; 115,455...

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發表在:Nat Genet
Main Authors: Klarin, Derek, Zhu, Qiuyu Martin, Emdin, Connor A., Chaffin, Mark, Horner, Steven, McMillan, Brian J., Leed, Alison, Weale, Michael E., Spencer, Chris C. A., Aguet, François, Segrè, Ayellet V., Ardlie, Kristin G., Khera, Amit V., Kaushik, Virendar K., Natarajan, Pradeep, Consortium, CARDIoGRAMplusC4D, Kathiresan, Sekar
格式: Artigo
語言:Inglês
出版: 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577383/
https://ncbi.nlm.nih.gov/pubmed/28714974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3914
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