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Nucleolar expansion and elevated protein translation in premature aging
Premature aging disorders provide an opportunity to study the mechanisms that drive aging. In Hutchinson-Gilford progeria syndrome (HGPS), a mutant form of the nuclear scaffold protein lamin A distorts nuclei and sequesters nuclear proteins. We sought to investigate protein homeostasis in this disea...
Sparad:
| I publikationen: | Nat Commun |
|---|---|
| Huvudupphovsmän: | , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Nature Publishing Group UK
2017
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5577202/ https://ncbi.nlm.nih.gov/pubmed/28855503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00322-z |
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