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The Chromatin-Associated Phf12 Protein Maintains Nucleolar Integrity and Prevents Premature Cellular Senescence

Pf1, also known as Phf12 (plant homeodomain [PHD] zinc finger protein 12), is a member of the PHD zinc finger family of proteins. Pf1 associates with a chromatin-interacting protein complex comprised of MRG15, Sin3B, and histone deacetylase 1 (HDAC1) that functions as a transcriptional modulator. Th...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Graveline, Richard, Marcinkiewicz, Katarzyna, Choi, Seyun, Paquet, Marilène, Wurst, Wolfgang, Floss, Thomas, David, Gregory
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5311238/
https://ncbi.nlm.nih.gov/pubmed/27956701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00522-16
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