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ASCIZ/ATMIN is dispensable for ATM signaling in response to replication stress

The ATM kinase plays critical roles in the response to DNA double-strand breaks, and can also be activated by prolonged DNA replication blocks. It has recently been proposed that replication stress-dependent ATM activation is mediated by ASCIZ (also known as ATMIN, ZNF822), an essential developmenta...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Liu, Rui, King, Ashleigh, Hoch, Nicolas C., Chang, Catherine, Kelly, Gemma L., Deans, Andrew J., Heierhorst, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576915/
https://ncbi.nlm.nih.gov/pubmed/28648892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2017.06.022
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