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ATMIN is required for the ATM-mediated signaling and recruitment of 53BP1 to DNA damage sites upon replication stress

Unresolved replication intermediates can block the progression of replication forks and become converted into DNA lesions, hence exacerbating genomic instability. The p53-binding protein 1 (53BP1) forms nuclear bodies at sites of unrepaired DNA lesions to shield these regions against erosion, in a m...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Schmidt, Luisa, Wiedner, Marc, Velimezi, Georgia, Prochazkova, Jana, Owusu, Michel, Bauer, Sabine, Loizou, Joanna I.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251980/
https://ncbi.nlm.nih.gov/pubmed/25262557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2014.09.001
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