DNA Repair Cofactors ATMIN and NBS1 Are Required to Suppress T Cell Activation

Proper development of the immune system is an intricate process dependent on many factors, including an intact DNA damage response. The DNA double-strand break signaling kinase ATM and its cofactor NBS1 are required during T cell development and for the maintenance of genomic stability. The role of...

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Vydáno v:PLoS Genet
Hlavní autoři: Prochazkova, Jana, Sakaguchi, Shinya, Owusu, Michel, Mazouzi, Abdelghani, Wiedner, Marc, Velimezi, Georgia, Moder, Martin, Turchinovich, Gleb, Hladik, Anastasiya, Gurnhofer, Elisabeth, Hayday, Adrian, Behrens, Axel, Knapp, Sylvia, Kenner, Lukas, Ellmeier, Wilfried, Loizou, Joanna I.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636180/
https://ncbi.nlm.nih.gov/pubmed/26544571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005645
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