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Dynamics of the DNA repair proteins WRN and BLM in the nucleoplasm and nucleoli
We have investigated the mobility of two EGFP-tagged DNA repair proteins, WRN and BLM. In particular, we focused on the dynamics in two locations, the nucleoli and the nucleoplasm. We found that both WRN and BLM use a “DNA-scanning” mechanism, with rapid binding–unbinding to DNA resulting in effecti...
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| Gepubliceerd in: | Eur Biophys J |
|---|---|
| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5576897/ https://ncbi.nlm.nih.gov/pubmed/25119658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00249-014-0981-x |
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