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The role of DNA base excision repair in brain homeostasis and disease

Chemical modification and spontaneous loss of nucleotide bases from DNA are estimated to occur at the rate of thousands per human cell per day. DNA base excision repair (BER) is a critical mechanism for repairing such lesions in nuclear and mitochondrial DNA. Defective expression or function of prot...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Akbari, Mansour, Morevati, Marya, Croteau, Deborah, Bohr, Vilhelm A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576892/
https://ncbi.nlm.nih.gov/pubmed/26002197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2015.04.029
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