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The Impact of Base Excision DNA Repair in Age-Related Neurodegenerative Diseases

The aging process and several age-related neurodegenerative disorders have been linked to elevated levels of DNA damage induced by ROS and deficiency in DNA repair mechanisms. DNA damage induced by ROS is a byproduct of cellular respiration and accumulation of damage over time, is a fundamental aspe...

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Detalhes bibliográficos
Publicado no:Mutat Res
Main Authors: Leandro, Giovana S., Sykora, Peter, Bohr, Vilhelm A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576886/
https://ncbi.nlm.nih.gov/pubmed/26255938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2014.12.011
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