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Permeability transition in human mitochondria persists in the absence of peripheral stalk subunits of ATP synthase
The opening of a nonspecific channel, known as the permeability transition pore (PTP), in the inner membranes of mitochondria can be triggered by calcium ions, leading to swelling of the organelle, disruption of the inner membrane and ATP synthesis, and cell death. Pore opening can be inhibited by c...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5576841/ https://ncbi.nlm.nih.gov/pubmed/28784775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1711201114 |
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