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Persistence of the mitochondrial permeability transition in the absence of subunit c of human ATP synthase

The permeability transition in human mitochondria refers to the opening of a nonspecific channel, known as the permeability transition pore (PTP), in the inner membrane. Opening can be triggered by calcium ions, leading to swelling of the organelle, disruption of the inner membrane, and ATP synthesi...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: He, Jiuya, Ford, Holly C., Carroll, Joe, Ding, Shujing, Fearnley, Ian M., Walker, John E.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380099/
https://ncbi.nlm.nih.gov/pubmed/28289229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1702357114
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