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Persistence of the mitochondrial permeability transition in the absence of subunit c of human ATP synthase

The permeability transition in human mitochondria refers to the opening of a nonspecific channel, known as the permeability transition pore (PTP), in the inner membrane. Opening can be triggered by calcium ions, leading to swelling of the organelle, disruption of the inner membrane, and ATP synthesi...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: He, Jiuya, Ford, Holly C., Carroll, Joe, Ding, Shujing, Fearnley, Ian M., Walker, John E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380099/
https://ncbi.nlm.nih.gov/pubmed/28289229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1702357114
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