Tumor engraftment in patient-derived xenografts of pancreatic ductal adenocarcinoma is associated with adverse clinicopathological features and poor survival

Patient-derived xenograft (PDX) tumors are powerful tools to study cancer biology. However, the ability of PDX tumors to model the biological and histological diversity of pancreatic ductal adenocarcinoma (PDAC) is not well known. In this study, we subcutaneously implanted 133 primary and metastatic...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Pergolini, Ilaria, Morales-Oyarvide, Vicente, Mino-Kenudson, Mari, Honselmann, Kim C., Rosenbaum, Matthew W., Nahar, Sabikun, Kem, Marina, Ferrone, Cristina R., Lillemoe, Keith D., Bardeesy, Nabeel, Ryan, David P., Thayer, Sarah P., Warshaw, Andrew L., Fernández-del Castillo, Carlos, Liss, Andrew S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576681/
https://ncbi.nlm.nih.gov/pubmed/28854237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182855
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