A fast, simple, and cost-effective method of expanding patient-derived xenograft mouse models of pancreatic ductal adenocarcinoma

BACKGROUND: Patient-derived xenograft (PDX) mouse models of cancer have been recognized as better mouse models that recapitulate the characteristics of original malignancies including preserved tumor heterogeneity, lineage hierarchy, and tumor microenvironment. However, common challenges of PDX mode...

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Библиографические подробности
Опубликовано в: :J Transl Med
Главные авторы: Liu, Zhenyang, Ahn, Michael Ho-Young, Kurokawa, Tomohiro, Ly, Amy, Zhang, Gong, Wang, Fuyou, Yamada, Teppei, Sadagopan, Ananthan, Cheng, Jane, Ferrone, Cristina R., Liss, Andrew S., Honselmann, Kim C., Wojtkiewicz, Gregory R., Ferrone, Soldano, Wang, Xinhui
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2020
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7315507/
https://ncbi.nlm.nih.gov/pubmed/32580742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02414-9
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