Tumor engraftment in patient-derived xenografts of pancreatic ductal adenocarcinoma is associated with adverse clinicopathological features and poor survival

Patient-derived xenograft (PDX) tumors are powerful tools to study cancer biology. However, the ability of PDX tumors to model the biological and histological diversity of pancreatic ductal adenocarcinoma (PDAC) is not well known. In this study, we subcutaneously implanted 133 primary and metastatic...

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Publicat a:PLoS One
Autors principals: Pergolini, Ilaria, Morales-Oyarvide, Vicente, Mino-Kenudson, Mari, Honselmann, Kim C., Rosenbaum, Matthew W., Nahar, Sabikun, Kem, Marina, Ferrone, Cristina R., Lillemoe, Keith D., Bardeesy, Nabeel, Ryan, David P., Thayer, Sarah P., Warshaw, Andrew L., Fernández-del Castillo, Carlos, Liss, Andrew S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576681/
https://ncbi.nlm.nih.gov/pubmed/28854237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182855
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