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LUBAC-synthesized linear ubiquitin chains restrict cytosol-invading bacteria by activating autophagy and NF-κB
Cell-autonomous immunity relies on the ubiquitin coat surrounding cytosol-invading bacteria functioning as an 'eat-me' signal for xenophagy. The origin, composition, and precise mode of action of the ubiquitin coat remain incompletely understood. Here, by studying Salmonella Typhimurium, w...
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| izdano v: | Nat Microbiol |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5576533/ https://ncbi.nlm.nih.gov/pubmed/28481331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmicrobiol.2017.63 |
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