Netrin1 produced by neural progenitors, not floor plate cells, is required for axon guidance in the spinal cord

Netrin1 has been proposed to act from the floor plate (FP) as a long-range diffusible chemoattractant for commissural axons in the embryonic spinal cord. However, netrin1 mRNA and protein are also present in neural progenitors within the ventricular zone (VZ), raising the question of which source of...

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Publicat a:Neuron
Autors principals: Varadarajan, Supraja G., Kong, Jennifer H., Phan, Keith D., Kao, Tzu-Jen, Panaitof, S. Carmen, Cardin, Julie, Eltzschig, Holger, Kania, Artur, Novitch, Bennett G., Butler, Samantha J.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576449/
https://ncbi.nlm.nih.gov/pubmed/28434801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2017.03.007
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