Netrin1 produced by neural progenitors, not floor plate cells, is required for axon guidance in the spinal cord

Netrin1 has been proposed to act from the floor plate (FP) as a long-range diffusible chemoattractant for commissural axons in the embryonic spinal cord. However, netrin1 mRNA and protein are also present in neural progenitors within the ventricular zone (VZ), raising the question of which source of...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Varadarajan, Supraja G., Kong, Jennifer H., Phan, Keith D., Kao, Tzu-Jen, Panaitof, S. Carmen, Cardin, Julie, Eltzschig, Holger, Kania, Artur, Novitch, Bennett G., Butler, Samantha J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576449/
https://ncbi.nlm.nih.gov/pubmed/28434801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2017.03.007
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