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Netrin-1 Derived from the Ventricular Zone, but not the Floor Plate, Directs Hindbrain Commissural Axons to the Ventral Midline

Netrin-1 (Ntn1) emanating from the ventral midline has been thought to act as a long-range diffusible chemoattractant for commissural axons (CAs). However, CAs still grow towards the midline in the absence of the floor plate (FP), a glial structure occupying the midline. Here, using genetically loss...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Yamauchi, Kenta, Yamazaki, Maya, Abe, Manabu, Sakimura, Kenji, Lickert, Heiko, Kawasaki, Takahiko, Murakami, Fujio, Hirata, Tatsumi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607380/
https://ncbi.nlm.nih.gov/pubmed/28931893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12269-8
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