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Hypoxia inducible factor (HIF) as a model for studying inhibition of protein–protein interactions
The modulation of protein–protein interactions (PPIs) represents a major challenge in modern chemical biology. Current approaches (e.g. high-throughput screening, computer aided ligand design) are recognised as having limitations in terms of identification of hit matter. Considerable success has bee...
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| Publicat a: | Chem Sci |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Royal Society of Chemistry
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5576430/ https://ncbi.nlm.nih.gov/pubmed/28878873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc00388a |
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