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Hypoxia inducible factor (HIF) as a model for studying inhibition of protein–protein interactions

The modulation of protein–protein interactions (PPIs) represents a major challenge in modern chemical biology. Current approaches (e.g. high-throughput screening, computer aided ligand design) are recognised as having limitations in terms of identification of hit matter. Considerable success has bee...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Chem Sci
मुख्य लेखकों: Burslem, George M., Kyle, Hannah F., Nelson, Adam, Edwards, Thomas A., Wilson, Andrew J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Royal Society of Chemistry 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576430/
https://ncbi.nlm.nih.gov/pubmed/28878873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc00388a
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