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FolamiRs: Ligand-targeted, vehicle-free delivery of microRNAs for the treatment of cancer

MicroRNAs are small RNAs that negatively regulate gene expression posttranscriptionally. Because changes in microRNA expression can promote or maintain disease states, microRNA-based therapeutics are being evaluated extensively. Unfortunately, the therapeutic potential of microRNA replacement is lim...

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Detalles Bibliográficos
Publicado en:Sci Transl Med
Autores principales: Orellana, Esteban A., Tenneti, Srinivasarao, Rangasamy, Loganathan, Lyle, L. Tiffany, Low, Philip S., Kasinski, Andrea L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576188/
https://ncbi.nlm.nih.gov/pubmed/28768807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aam9327
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