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FolamiRs: Ligand-targeted, vehicle-free delivery of microRNAs for the treatment of cancer

MicroRNAs are small RNAs that negatively regulate gene expression posttranscriptionally. Because changes in microRNA expression can promote or maintain disease states, microRNA-based therapeutics are being evaluated extensively. Unfortunately, the therapeutic potential of microRNA replacement is lim...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Orellana, Esteban A., Tenneti, Srinivasarao, Rangasamy, Loganathan, Lyle, L. Tiffany, Low, Philip S., Kasinski, Andrea L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576188/
https://ncbi.nlm.nih.gov/pubmed/28768807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aam9327
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