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Enhancing MicroRNA Activity through Increased Endosomal Release Mediated by Nigericin

The therapeutic promise of small-RNA therapeutics is limited, not only by the lack of delivery vehicles, but also by the inability of the small RNAs to reach intracellular compartments where they can be biologically active. We previously reported successful delivery of functionally active miRNAs via...

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Bibliografiset tiedot
Julkaisussa:Mol Ther Nucleic Acids
Päätekijät: Orellana, Esteban A., Abdelaal, Ahmed M., Rangasamy, Loganathan, Tenneti, Srinivasarao, Myoung, Sunghyun, Low, Philip S., Kasinski, Andrea L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Gene & Cell Therapy 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506612/
https://ncbi.nlm.nih.gov/pubmed/31071527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.04.003
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